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KMID : 1114620050020010015
Journal of the Korean Society for Breast Screening
2005 Volume.2 No. 1 p.15 ~ p.20
The Sensitivity of Computer-aided Detection in Digital Mammograms: Comparison of Ultrasound-detected Cancers and Mammographically Detected Cancers
Yang Sang-Kyu

Kim Seung-Ja
Cho Nariya
Moon Woo-Kyung
Abstract
Purpose: To compare the sensitivity of mammographic computer-aided detection (CAD) system in breast cancer detected only by ultrasonography (US) and those in breast cancers detected by screening mammography.

Materials and Methods: The CAD system (ImageChecker M1000-DM, version 3.1; R2 Technology) embedded in full-field digital mammography (Senographe 2000D; GE Medical Systems) was prospectively applied to the mammograms of 71 patients (age range 36-69 years, mean age 56.4 years) with nonpalpable breast cancers. The US group (26 patients having 29 cancers) consisted of patients with screening US detected breast cancer and normal mammographic findings, even in retrospect. The mammography group (70 patients having 70 cancers) consisted of patients with screening mammography detected breast cancer. Mean tumor size of US and mammographically detected cancers was 1.1 cm and 1.9 cm, respectively. The sensitivity, and false positive marks rate of the CAD system were determined for the two groups.

Results: In US group, the CAD system correctly detected the cancer on mammograms in 5/29 cases (17.2%). In mammography group, the CAD system correctly detected the cancer on mammography in 67/70 cases (95.7%). False positive marks rate was 0.68 per image for US-detected cancers and 0.35 per image for mammography-detected cancers.

Conclusion: The CAD system depicted only 17% of US detected cancers whereas the CAD system depicted about 96% of mammographically detected cancers.
KEYWORD
Breast cancer, Mammography, Breast ultrasound, Computer-aided detection
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